Phosphate homeostasis, monitoring and managment of hyperphosphatemia in patients with the Chronic Kidney diseases

2. Sodium-dependent Pi co-transporters

Absorption of phosphate is mediated by the brush border sodium-dependent Pi co-transporters (NPT), which depend on the Na/K-dependent ATPase. There are three classes of these co-transporters.


Richard J. Johnson & John Feehally & Jurgen Floege & Marcello Tonelli.  Comprehensive Clinical Nephrology. Elsevier, Edinburgh, 2019