Phosphate homeostasis, monitoring and managment of hyperphosphatemia in patients with the Chronic Kidney diseases

This section presents material on the significance of hyperphosphatemia in patients with CKD, Dietary Therapy for Managing Hyperphosphatemia

2. Sodium-dependent Pi co-transporters

Absorption of phosphate is mediated by the brush border sodium-dependent Pi co-transporters (NPT), which depend on the Na/K-dependent ATPase. There are three classes of these co-transporters.


Richard J. Johnson & John Feehally & Jurgen Floege & Marcello Tonelli.  Comprehensive Clinical Nephrology. Elsevier, Edinburgh, 2019